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Med Oncol. Embryonic signature in breast cancers; Pluripotency roots of cancer stem cells. Notch1 signaling is activated in cells expressing embryonic stem cell proteins in human primary nasopharyngeal carcinoma. Notch signaling pathway The NOTCH gene was firstly discovered in Drosophila , in which partial loss of function of this gene caused a notch of the wing edge. Type Straight Gay Shemale.

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Lab Invest. Sox2 is expressed not only in ESCs, but also in several other types of stem cells, including neural stem cells, and it regulates the progress of primary neurogenesis, neural development and neural differentiation. SOX2 targets fibronectin 1 to promote cell migration and invasion in ovarian cancer: Cytogenet Genome Res.

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